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  6. Invitrogen™ Procollagen I N-Peptide Monoclonal Antibody (C8), Invitrogen™

Invitrogen™ Procollagen I N-Peptide Monoclonal Antibody (C8), Invitrogen™
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Catalog No. FEMA551183
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200 μL
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FEMA551183 200 μL
FEMA551184 20 μL
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Catalog No. FEMA551183 Supplier Invitrogen™ Supplier No. MA551183
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Description

Mouse Monoclonal Antibody

Procollagen type I N-terminal propeptide (P1NP) is a specific marker of bone formation, reflecting the synthesis of type I collagen, which constitutes the major part of the bone matrix. P1NP is derived during the conversion of procollagen to collagen, produced by osteoblasts during bone formation. Its primary clinical application lies in the diagnosis and monitoring of metabolic bone diseases, particularly osteoporosis. In osteoporotic patients, P1NP levels can predict bone mineral density (BMD) responses to treatments like teriparatide and romosozumab. Low serum levels of P1NP are indicative of a high risk of BMD loss, providing a valuable tool for premenopausal women with systemic lupus erythematosus (SLE) and other conditions affecting bone health.
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Specifications

Antigen Procollagen I N-Peptide
Applications Immunohistochemistry (Paraffin), Western Blot, Western Blot
Classification Monoclonal
Clone C8
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
Gene COL1A1
Gene Accession No. P02452, P02454
Gene Alias P1NP; Procollagen I N
Gene Symbols COL1A1
Host Species Mouse
Immunogen KLH conjugated Human PINP protein (Accession #P02452).
Purification Method Protein A/G
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1277, 29393
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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