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Invitrogen™ Procollagen I N-Peptide Monoclonal Antibody (H20), Invitrogen™
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Catalog No. PIMA543884
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100 μL
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PIMA543884 100 μL
PIMA543885 20 μL
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Catalog No. PIMA543884 Supplier Invitrogen™ Supplier No. MA543884
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Description

Mouse Monoclonal Antibody

Procollagen type I N-terminal propeptide (P1NP) is a specific marker of bone formation, reflecting the synthesis of type I collagen, which constitutes the major part of the bone matrix. P1NP is derived during the conversion of procollagen to collagen, produced by osteoblasts during bone formation. Its primary clinical application lies in the diagnosis and monitoring of metabolic bone diseases, particularly osteoporosis. In osteoporotic patients, P1NP levels can predict bone mineral density (BMD) responses to treatments like teriparatide and romosozumab. Low serum levels of P1NP are indicative of a high risk of BMD loss, providing a valuable tool for premenopausal women with systemic lupus erythematosus (SLE) and other conditions affecting bone health.
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Specifications

Antigen Procollagen I N-Peptide
Applications Western Blot
Classification Monoclonal
Clone H20
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene COL1A1
Gene Accession No. P02452
Gene Alias P1NP; Procollagen I N
Gene Symbols COL1A1
Host Species Mouse
Immunogen Recombinant PINP (Gln23-Pro161) expressed in E.coli.
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1277
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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