Invitrogen™ Profilin 1 Recombinant Rabbit Monoclonal Antibody (2Z1M4)

Catalog No.	Quantity
PIMA535775	100 μL

Catalog No. PIMA535775 Supplier Invitrogen™ Supplier No. MA535775

Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: VNGLTLGGQK CSVIRDSLLQ DGEFSMDLRT KSTGGAPTFN VTVTKTDKTL VLLMGKEGVH GGLINKKCYE MASHLRRSQY.

Profilin is an ubiquitous small (12-15 kDa) phosphoinositides and poly-L-proline binding protein that plays a role in both signal transduction pathways and actin filament dynamics. There are two mammalian profilins with similar biochemical properties but different expression patterns. Profilin I appears to be highly expressed in most tissues except for skeletal muscle. Profilin II is predominantly expressed in brain and at lower levels in skeletal muscle, uterus and kidney. Profilin is a mainly cytosolic protein with higher concentrations in dynamic membrane areas like the leading edge and ruffling membranes.

Specifications

• Antigen: Profilin 1
• Applications: ELISA, Western Blot
• Classification: Recombinant Monoclonal
• Clone: 2Z1M4
• Concentration: 0.31 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: Pfn1
• Gene Accession No.: P07737, P62962, P62963
• Gene Alias: actin binding protein; ALS18; Epididymis tissue protein Li 184a; Pfn; Pfn1; profilin 1; profilin I; Profilin-1
• Gene Symbols: Pfn1
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 61-140 of human PFN1 (P07737).
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 18643, 5216, 64303
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG