Invitrogen™ Profilin 1 Monoclonal Antibody (CL3524)

Catalog No.	Quantity
PIMA531386	100 μL

Catalog No. PIMA531386

Supplier: Invitrogen™ MA531386

Description

Mouse Monoclonal Antibody

Immunogen sequence: KSIGGAPTFN VTVTKTDKTL VLLMGKEGIH G Highest antigen sequence indentity to the following orthologs: Mouse - 87%, Rat - 87%.

Profilin is an ubiquitous small (12-15 kDa) phosphoinositides and poly-L-proline binding protein that plays a role in both signal transduction pathways and actin filament dynamics. There are two mammalian profilins with similar biochemical properties but different expression patterns. Profilin I appears to be highly expressed in most tissues except for skeletal muscle. Profilin II is predominantly expressed in brain and at lower levels in skeletal muscle, uterus and kidney. Profilin is a mainly cytosolic protein with higher concentrations in dynamic membrane areas like the leading edge and ruffling membranes.

Specifications

• Antigen: Profilin 1
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: CL3524
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: Pfn1
• Gene Accession No.: P07737
• Gene Alias: actin binding protein; ALS18; Epididymis tissue protein Li 184a; Pfn; Pfn1; profilin 1; profilin I; Profilin-1
• Gene Symbols: Pfn1
• Host Species: Mouse
• Immunogen: Recombinant protein fragment of Human PFN1 (Product #RP-108174)
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5216
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a