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Invitrogen™ Profilin 1 Monoclonal Antibody (CL3524)
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Catalog No. PIMA531386
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100 μL
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PIMA531386 100 μL
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Catalog No. PIMA531386 Supplier Invitrogen™ Supplier No. MA531386
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Mouse Monoclonal Antibody

Immunogen sequence: KSIGGAPTFN VTVTKTDKTL VLLMGKEGIH G Highest antigen sequence indentity to the following orthologs: Mouse - 87%, Rat - 87%.

Profilin is an ubiquitous small (12-15 kDa) phosphoinositides and poly-L-proline binding protein that plays a role in both signal transduction pathways and actin filament dynamics. There are two mammalian profilins with similar biochemical properties but different expression patterns. Profilin I appears to be highly expressed in most tissues except for skeletal muscle. Profilin II is predominantly expressed in brain and at lower levels in skeletal muscle, uterus and kidney. Profilin is a mainly cytosolic protein with higher concentrations in dynamic membrane areas like the leading edge and ruffling membranes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Profilin 1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone CL3524
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Pfn1
Gene Accession No. P07737
Gene Alias actin binding protein; ALS18; Epididymis tissue protein Li 184a; Pfn; Pfn1; profilin 1; profilin I; Profilin-1
Gene Symbols Pfn1
Host Species Mouse
Immunogen Recombinant protein fragment of Human PFN1 (Product #RP-108174)
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5216
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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