Invitrogen™ Profilin 1 Polyclonal Antibody

Catalog No.	Quantity
PIPA522991	100 μL

Catalog No. PIPA522991 Supplier Invitrogen™ Supplier No. PA522991

Description

Rabbit Polyclonal Antibody

Suggested positive control: human brain lysate.

Profilin is an ubiquitous small (12-15 kDa) phosphoinositides and poly-L-proline binding protein that plays a role in both signal transduction pathways and actin filament dynamics. There are two mammalian profilins with similar biochemical properties but different expression patterns. Profilin I appears to be highly expressed in most tissues except for skeletal muscle. Profilin II is predominantly expressed in brain and at lower levels in skeletal muscle, uterus and kidney. Profilin is a mainly cytosolic protein with higher concentrations in dynamic membrane areas like the leading edge and ruffling membranes.

Specifications

• Antigen: Profilin 1
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1.17 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 30% glycerol and 0.1% sodium azide
• Gene: Pfn1
• Gene Accession No.: P02584, P07737, P62962, P62963
• Gene Alias: actin binding protein; ALS18; Epididymis tissue protein Li 184a; Pfn; Pfn1; profilin 1; profilin I; Profilin-1
• Gene Symbols: Pfn1
• Host Species: Rabbit
• Immunogen: Synthetic peptide made to a C-terminal portion of human Profilin 1 (within residues 100-140).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 18643, 513895, 5216, 64303
• Target Species: Human, Mouse, Rat, Bovine
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG