Invitrogen™ Progesterone Monoclonal Antibody (2D9)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA549665

Catalog No. PIMA549665

Description

Antibody tested in indirect ELISA.

Progesterone is the major progestational steroid, secreted primarily by the corpus luteum and the placenta. Progesterone binds to the progesterone receptor, resulting in dissociation of heat shock proteins, receptor phosphorylation, and transcription activation through direct or indirect interaction with transcription factors. Progesterone acts on the uterus, the mammary glands and the brain. It is required in embryo implantation, pregnancy maintenance, and the development of mammary tissue for milk production. Progesterone, converted from pregnenolone, also serves as an intermediate in the biosynthesis of gonadal steroid hormones and adrenal corticosteroids. Therapeutic progesterone is a synthetic form of the endogenous hormone progesterone. This agent exerts inhibitory effects on estrogens by decreasing the number of estrogen receptors and increasing its metabolism to inactive metabolites. [National Center for Biotechnology Information. PubChem Compound Database; CID=5994].

Specifications

• Antigen: Progesterone
• Classification: Monoclonal
• Concentration: 7.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Target Species: Chemical
• Product Type: Antibody
• Isotype: IgG1 λ

• Applications: ELISA, Immunohistochemistry, Lateral Flow, SDS-Page
• Clone: 2D9
• Conjugate: Unconjugated
• Gene Alias: 11-alpha-hydroxyprogesterone; Agolutin; C21H30O2; Crinone; Luteohormone; OHP; Pregn-4-ene-3; Progesterone-11a-hemisuccinate
• Immunogen: Conjugate of P hapten and KLH.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid