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Invitrogen™ Progesterone Monoclonal Antibody (BGN/6-5E-10B)
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Catalog No. PIMA183407
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PIMA183407 1 mg
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Catalog No. PIMA183407 Supplier Invitrogen™ Supplier No. MA183407
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Description

Mouse Monoclonal Antibody

MA1-83407 has the following specificities: Progesterone-11a-HMS-BSA - 100% , 5-beta-Pregnane-3,20-dione - 48%, 5-alpha-Pregnane-3,20-dione - 26.4%, 17-alpha-Hydroxyprogesterone - 2.5%, 20-alpha-Hydroxyprogesterone - 0.04%. Mouse anti Progesterone antibody, clone BGN/6-5E-10B has the following specificities: Progesterone-11a-HMS-BSA 100%, 5-beta-Pregnane-3,20-dione 48%, 5-alpha-Pregnane-3,20-dione 26.4%, 17-alpha-Hydroxyprogesterone 2.5%, 20-alpha Hydroxyprogesterone 0.04%.

Progesterone is the major progestational steroid, secreted primarily by the corpus luteum and the placenta. Progesterone binds to the progesterone receptor, resulting in dissociation of heat shock proteins, receptor phosphorylation, and transcription activation through direct or indirect interaction with transcription factors. Progesterone acts on the uterus, the mammary glands and the brain. It is required in embryo implantation, pregnancy maintenance, and the development of mammary tissue for milk production. Progesterone, converted from pregnenolone, also serves as an intermediate in the biosynthesis of gonadal steroid hormones and adrenal corticosteroids. Therapeutic progesterone is a synthetic form of the endogenous hormone progesterone. This agent exerts inhibitory effects on estrogens by decreasing the number of estrogen receptors and increasing its metabolism to inactive metabolites. [National Center for Biotechnology Information. PubChem Compound Database; CID=5994].
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Specifications

Antigen Progesterone
Applications ELISA, Radioimmune Assays (RIA)
Classification Monoclonal
Clone BGN/6-5E-10B
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene Alias 11-alpha-hydroxyprogesterone; Agolutin; C21H30O2; Crinone; Luteohormone; OHP; Pregn-4-ene-3; Progesterone-11a-hemisuccinate
Host Species Mouse
Immunogen Progesterone- 11a-hemisuccinate conjugated to bovine serum albumin (Pr11a-HMS-BSA).
Purification Method Protein A
Quantity 1 mg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Chemical
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
Target Molecule Chemical
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