Progesterone R/NR3C3 Antibody (PR484), Alexa Fluor™ 532, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP233325AF532

Catalog No. NP23332A32

Description

Progesterone R/NR3C3 Monoclonal specifically detects Progesterone R/NR3C3 in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: Progesterone R/NR3C3
• Classification: Monoclonal
• Conjugate: Alexa Fluor 532
• Formulation: 50 mM sodium borate with 0.05% sodium azide
• Gene Symbols: PGR
• Immunogen: Recombinant full-length human Progesterone R/NR3C3 protein (PGR) (Uniprot: P06401 )
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: This monoclonal antibody is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone. It is excellent for immunohistochemical staining of formalin/paraffin tissues.
• Content And Storage: Store at 4°C in the dark.

• Applications: Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunocytochemistry, Immunofluorescence
• Clone: PR484
• Dilution: Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
• Gene Alias: NR3C3PRNuclear receptor subfamily 3 group C member 3, progesterone receptor
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Research Discipline: Breast Cancer, Cancer, Phospho Specific
• Gene ID (Entrez): 5241.0
• Target Species: Human
• Isotype: IgG1 κ