Progesterone R/NR3C3 Antibody (PR484) - Azide and BSA Free, Novus Biologicals™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
NBP23332501	Novus Biologicals NBP2333250.1MG	0.1 mg
NBP23332502	Novus Biologicals NBP2333250.2MG	0.2 mg

Description

Progesterone R/NR3C3 Monoclonal specifically detects Progesterone R/NR3C3 in Human samples. It is validated for Simple Western, Immunohistochemistry, Immunohistochemistry-Paraffin, CyTOF-ready.

Specifications

• Antigen: Progesterone R/NR3C3
• Concentration: 1.0 mg/mL
• Applications: Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Mouse
• Research Discipline: Breast Cancer, Cancer
• Formulation: 10mM PBS - BSA free with No Preservative
• Gene ID (Entrez): 5241
• Immunogen: A progesterone receptor recombinant protein was used as the immunogen for the antibody. The specific epitope has not been mapped.
• Primary or Secondary: Primary
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

• Clone: PR484
• Dilution: Western Blot 0.5-1.0ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml, CyTOF-ready
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Target Species: Human
• Gene Alias: NR3C3PRNuclear receptor subfamily 3 group C member 3, progesterone receptor
• Gene Symbols: PGR
• Isotype: IgG1 κ
• Purification Method: Protein G purified
• Test Specificity: This MAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone. It is excellent for immunohistochemical staining of formalin/paraffin tissues.

For Research Use Only