Progesterone R/NR3C3 Antibody (SPM566), Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2343820.02MG

Catalog No. NBP234382F

Description

Progesterone R/NR3C3 Monoclonal specifically detects Progesterone R/NR3C3 in Human samples. It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: Progesterone R/NR3C3
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
• Gene Alias: NR3C3PRNuclear receptor subfamily 3 group C member 3, progesterone receptor
• Host Species: Mouse
• Purification Method: Protein A purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: This MAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone. It is excellent for immunohistochemical staining of formalin/paraffin tissues.
• Content And Storage: Store at 4C.
• Isotype: IgG1 κ

• Applications: Western Blot, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
• Clone: SPM566
• Dilution: Western Blot 0.5-1ug/ml, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml
• Gene Accession No.: P06401
• Gene Symbols: PGR
• Immunogen: Recombinant human Progesterone Receptor protein
• Quantity: 0.02 mg
• Research Discipline: Breast Cancer, Cancer
• Gene ID (Entrez): 5241
• Target Species: Human
• Form: Purified