Invitrogen™ Progesterone Monoclonal Antibody (2H4)

Rat Monoclonal Antibody

Supplier:  Invitrogen™ MA124904

Catalog No. PIMA124904

Description

MA1-24904 detects Progesterone from human samples.

Progesterone is the major progestational steroid, secreted primarily by the corpus luteum and the placenta. Progesterone binds to the progesterone receptor, resulting in dissociation of heat shock proteins, receptor phosphorylation, and transcription activation through direct or indirect interaction with transcription factors. Progesterone acts on the uterus, the mammary glands and the brain. It is required in embryo implantation, pregnancy maintenance, and the development of mammary tissue for milk production. Progesterone, converted from pregnenolone, also serves as an intermediate in the biosynthesis of gonadal steroid hormones and adrenal corticosteroids. Therapeutic progesterone is a synthetic form of the endogenous hormone progesterone. This agent exerts inhibitory effects on estrogens by decreasing the number of estrogen receptors and increasing its metabolism to inactive metabolites. [National Center for Biotechnology Information. PubChem Compound Database; CID=5994].

Specifications

• Antigen: Progesterone
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: Tissue culture supernatant with 15mM sodium azide
• Gene Accession No.: P06401
• Gene Symbols: PGR
• Immunogen: Progesterone-7-BSA.
• Regulatory Status: RUO
• Gene ID (Entrez): 5241
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Radioimmune Assays (RIA)
• Clone: 2H4
• Conjugate: Unconjugated
• Gene: PGR
• Gene Alias: 11-alpha-hydroxyprogesterone; Agolutin; C21H30O2; Crinone; Luteohormone; OHP; Pregn-4-ene-3; Progesterone-11a-hemisuccinate
• Host Species: Rat
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1