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Prohibitin Monoclonal Antibody (II-14-10), Biotin, Invitrogen™

Catalog No. PIMA512855
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Catalog No. Quantity
PIMA512855 500 μL
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Catalog No. PIMA512855 Supplier Thermo Scientific Supplier No. MA512855
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Description

Mouse Monoclonal Antibody

MA5-12855 targets Prohibitin in IF, IHC (P), and WB applications and shows reactivity with Chicken, Human, mouse, Porcine, and Rat samples. The MA5-12855 immunogen is purified recombinant rat prohibitin protein.

Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Prohibitin
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone II-14-10
Concentration 0.2 mg/mL
Conjugate Biotin
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene PHB
Gene Accession No. P35232, P67778, P67779, P84173
Gene Alias BAP 32; Bap32; B-cell receptor-associated protein 32; epididymis luminal protein 215; epididymis secretory sperm binding protein Li 54e; fa18f07; fb09f05; HEL-215; HEL-S-54e; OTTHUMP00000165765; OTTHUMP00000165766; OTTHUMP00000220103; OTTHUMP00000220170; OTTHUMP00000220171; PHB; phb protein; PHB1; Prohibitin; sr:nyz128; wu:fa18f07; wu:fb09f05
Gene Symbols PHB
Host Species Mouse
Immunogen Purified recombinant rat prohibitin protein
Purification Method Protein G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100524707, 18673, 25344, 419980, 5245
Target Species Chicken, Human, Mouse, Non-human Primate, Pig, Rat
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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