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Invitrogen™ Prohibitin Polyclonal Antibody
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Catalog No. PIPA587348
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100 μL
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PIPA587348 100 μL
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Catalog No. PIPA587348 Supplier Invitrogen™ Supplier No. PA587348
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Description

Rabbit Polyclonal Antibody

Positive Samples: Raji, NIH/3T3, HeLa, MCF7, HepG2, Mouse liver, Mouse heart, Mouse kidney, Rat heart; Cellular Location: Mitochondrion inner membrane Immunogen sequence: PRNVPVITGS KDLQNVNITL RILFRPVASQ LPRIFTSIGE DYDERVLPSI TTEILKSVVA RFDAGELITQ RELVSRQVSD DLTERAATFG LILDDVSLTH LTFGKEFTEA VEAKQVAQQE AERARFVVEK AEQQKKAAII SAEGDSKAAE LIANSLATAG DGLIELRKLE AAEDIAYQLS RSRNITYLPA GQSVLLQLPQ.

Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Prohibitin
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.36 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene PHB
Gene Accession No. P35232, P67778, P67779
Gene Alias BAP 32; Bap32; B-cell receptor-associated protein 32; epididymis luminal protein 215; epididymis secretory sperm binding protein Li 54e; fa18f07; fb09f05; HEL-215; HEL-S-54e; OTTHUMP00000165765; OTTHUMP00000165766; OTTHUMP00000220103; OTTHUMP00000220170; OTTHUMP00000220171; PHB; phb protein; PHB1; Prohibitin; sr:nyz128; wu:fa18f07; wu:fb09f05
Gene Symbols PHB
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 73-272 of human Prohibitin (NP_0026251).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18673, 25344, 5245
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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