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Invitrogen™ Prohibitin Polyclonal Antibody
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Catalog No. PIPA519556
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100 μg
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Catalog No. Quantity
PIPA519556 100 μg
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Catalog No. PIPA519556 Supplier Invitrogen™ Supplier No. PA519556
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Description

Rabbit Polyclonal Antibody

PA5-19556 targets Prohibitin in immunofluorescence, immunohistochemistry (paraffin), and Western blot applications and shows reactivity with Bovine, Canine, Human, mouse, and Rat samples. The PA5-19556 immunogen is synthetic peptide conjugated to KLH derived from within residues 200 - 300 of Human Prohibitin. PA5-19556 detects Prohibitin which has a predicted molecular weight of approximately 30 kDa.

Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Prohibitin
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.9 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA and 0.02% sodium azide; pH 7.4
Gene PHB
Gene Accession No. P35232, P67778, P67779
Gene Alias BAP 32; Bap32; B-cell receptor-associated protein 32; epididymis luminal protein 215; epididymis secretory sperm binding protein Li 54e; fa18f07; fb09f05; HEL-215; HEL-S-54e; OTTHUMP00000165765; OTTHUMP00000165766; OTTHUMP00000220103; OTTHUMP00000220170; OTTHUMP00000220171; PHB; phb protein; PHB1; Prohibitin; sr:nyz128; wu:fa18f07; wu:fb09f05
Gene Symbols PHB
Host Species Rabbit
Immunogen Synthetic peptide conjugated to KLH derived from within residues 200 - 300 of Human Prohibitin.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18673, 25344, 5245
Target Species Human, Mouse, Rat, Mouse, Pig, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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