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Invitrogen™ Prohibitin Recombinant Rabbit Monoclonal Antibody (SR46-02)
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Catalog No. PIMA532000
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PIMA532000 100 μL
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Catalog No. PIMA532000 Supplier Invitrogen™ Supplier No. MA532000
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Description

Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Prohibitin
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
Classification Recombinant Monoclonal
Clone SR46-02
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 40% Glycerol, 0.05% BSA and 0.05% sodium azide; pH 7.4
Gene PHB
Gene Accession No. P35232, P67778, P67779
Gene Alias BAP 32; Bap32; B-cell receptor-associated protein 32; epididymis luminal protein 215; epididymis secretory sperm binding protein Li 54e; fa18f07; fb09f05; HEL-215; HEL-S-54e; OTTHUMP00000165765; OTTHUMP00000165766; OTTHUMP00000220103; OTTHUMP00000220170; OTTHUMP00000220171; PHB; phb protein; PHB1; Prohibitin; sr:nyz128; wu:fa18f07; wu:fb09f05
Gene Symbols PHB
Host Species Rabbit
Immunogen Synthetic peptide within Human Prohibitin aa 147-196.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18673, 25344, 321346, 5245
Target Species Human, Mouse, Rat, Zebrafish
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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