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Invitrogen™ PROK2 Polyclonal Antibody
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Catalog No. PIPA5110221
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100 μL
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PIPA5110221 100 μL
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Catalog No. PIPA5110221 Supplier Invitrogen™ Supplier No. PA5110221
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Rabbit Polyclonal Antibody

Immunogen sequence: LTPRAGDAAV ITGACDKDSQ CGGGMCCAVS IWVKSIRICT PMGKLGDSCH PLTRKNNFGN GRQERRKRKR SKRKKEVPFF GRRMHHTCPC LPGLACLRTS FNRFICLAQK.

Prokineticin-2 (PK2) is a cysteine-rich secreted protein that is expressed in the suprachiasmatic nucleus (SCN) with receptors located in the critical autonomic control centers of the brain. It has a depolarizing effect on neurons expressing the receptor. PK2 is predominantly controlled by the endogenous circadian clock, but light also plays a modulatory role. PK2 functions as a critical SCN output molecule responsible for circadian locomotor rhythms. PK2 expression is high during the day, and responsive to nocturnal light pulses. PK2 also functions as a chemoattractant for subventricular zone-derived neuronal progenitors.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PROK2
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.87 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PROK2
Gene Accession No. Q8R413, Q9HC23, Q9QXU7
Gene Alias Bombina variegata 8 kD protein; Bombina variegata 8kDa protein; Bv 8 homolog (Bombina variegata); BV8; Bv8/prokineticin 2-like protein; Bv8/prokineticin 2-like protein splice variant; HH4; homolog of mouse Bv8 (Bombina variegata 8 kDa); homolog of mouse Bv8 (Bombina variegata 8 kDa); prokineticin 2; KAL4; MIT1; PK2; Prok1; Prok2; prokineticin 1; prokineticin 2; prokineticin 2 beta; prokineticin-2; Protein Bv8 homolog; secreted protein
Gene Symbols PROK2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 20-129 of human PROK2 (NP_001119600.1).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 192206, 50501, 60675
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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