Invitrogen™ PROK2 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA5142524

Catalog No. PIPA5142524

Description

Additional Information: This antibody is expected to recognize isoform a (NP_001119600.1). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000. Preliminary analysis showed no signal in Western Blot.

Prokineticin-2 (PK2) is a cysteine-rich secreted protein that is expressed in the suprachiasmatic nucleus (SCN) with receptors located in the critical autonomic control centers of the brain. It has a depolarizing effect on neurons expressing the receptor. PK2 is predominantly controlled by the endogenous circadian clock, but light also plays a modulatory role. PK2 functions as a critical SCN output molecule responsible for circadian locomotor rhythms. PK2 expression is high during the day, and responsive to nocturnal light pulses. PK2 also functions as a chemoattractant for subventricular zone-derived neuronal progenitors.

Specifications

• Antigen: PROK2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PROK2
• Gene Alias: Bombina variegata 8 kD protein; Bombina variegata 8kDa protein; Bv 8 homolog (Bombina variegata); BV8; Bv8/prokineticin 2-like protein; Bv8/prokineticin 2-like protein splice variant; HH4; homolog of mouse Bv8 (Bombina variegata 8 kDa); homolog of mouse Bv8 (Bombina variegata 8 kDa); prokineticin 2; KAL4; MIT1; PK2; Prok1; Prok2; prokineticin 1; prokineticin 2; prokineticin 2 beta; prokineticin-2; Protein Bv8 homolog; secreted protein
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 60675
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9HC23
• Gene Symbols: PROK2
• Immunogen: Peptide with sequence C-HPLTRKNNFGNGRQE.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG