Invitrogen™ PROK2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA570630

Catalog No. PIPA570630

Description

This target displays homology in the following species: Cow: 85%; Human: 100%; Mouse: 79%; Pig: 86%; Rat: 86%.

Prokineticin-2 (PK2) is a cysteine-rich secreted protein that is expressed in the suprachiasmatic nucleus (SCN) with receptors located in the critical autonomic control centers of the brain. It has a depolarizing effect on neurons expressing the receptor. PK2 is predominantly controlled by the endogenous circadian clock, but light also plays a modulatory role. PK2 functions as a critical SCN output molecule responsible for circadian locomotor rhythms. PK2 expression is high during the day, and responsive to nocturnal light pulses. PK2 also functions as a chemoattractant for subventricular zone-derived neuronal progenitors.

Specifications

• Antigen: PROK2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PROK2
• Gene Alias: Bombina variegata 8 kD protein; Bombina variegata 8kDa protein; Bv 8 homolog (Bombina variegata); BV8; Bv8/prokineticin 2-like protein; Bv8/prokineticin 2-like protein splice variant; HH4; homolog of mouse Bv8 (Bombina variegata 8 kDa); homolog of mouse Bv8 (Bombina variegata 8 kDa); prokineticin 2; KAL4; MIT1; PK2; Prok1; Prok2; prokineticin 1; prokineticin 2; prokineticin 2 beta; prokineticin-2; Protein Bv8 homolog; secreted protein
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 60675
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9HC23
• Gene Symbols: PROK2
• Immunogen: synthetic peptide directed towards the middle region of human PROK2 (aa 53-102).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG