Invitrogen™ PROK2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA576994

Catalog No. PIPA576994

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Prokineticin-2 (PK2) is a cysteine-rich secreted protein that is expressed in the suprachiasmatic nucleus (SCN) with receptors located in the critical autonomic control centers of the brain. It has a depolarizing effect on neurons expressing the receptor. PK2 is predominantly controlled by the endogenous circadian clock, but light also plays a modulatory role. PK2 functions as a critical SCN output molecule responsible for circadian locomotor rhythms. PK2 expression is high during the day, and responsive to nocturnal light pulses. PK2 also functions as a chemoattractant for subventricular zone-derived neuronal progenitors.

Specifications

• Antigen: PROK2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PROK2
• Gene Alias: Bombina variegata 8 kD protein; Bombina variegata 8kDa protein; Bv 8 homolog (Bombina variegata); BV8; Bv8/prokineticin 2-like protein; Bv8/prokineticin 2-like protein splice variant; HH4; homolog of mouse Bv8 (Bombina variegata 8 kDa); homolog of mouse Bv8 (Bombina variegata 8 kDa); prokineticin 2; KAL4; MIT1; PK2; Prok1; Prok2; prokineticin 1; prokineticin 2; prokineticin 2 beta; prokineticin-2; Protein Bv8 homolog; secreted protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 192206, 50501, 60675
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8R413, Q9HC23, Q9QXU7
• Gene Symbols: PROK2
• Immunogen: Recombinant full length Human PROK2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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