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Invitrogen™ Prolactin Receptor Monoclonal Antibody (A6E4)
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Catalog No. FEMA550553
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100 μL
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Catalog No. Quantity
FEMA550553 100 μL
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Catalog No. FEMA550553 Supplier Invitrogen™ Supplier No. MA550553
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Description

Mouse Monoclonal Antibody

Positive control: 293T cell lysate, Hela cell lysate, MCF-7, human kidney tissue, human pancreas tissue. Predicted band size: 70 kDa Subcellular Location: Membrane, Secreted.

Prolactin (PRL) is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. PRL exerts its influence on different cell types through a signal transduction pathway which begins with the binding of the hormone to a transmembrane PRL receptor. Immunoreactive PRL receptor (PRLR), a member of the cytokine receptor family, varies in size (short and long forms) with tissue source and species, from ~40 kDa to 100 kDa. PRLR consists of at least three separate domains: an extracellular region with 5 cysteines which contains the prolactin binding site, a single transmembrane domain and a cytoplasmic region, the length of which appears to influence ligand binding and regulate cellular function.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Prolactin Receptor
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone A6E4
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene PRLR
Gene Accession No. P16471
Gene Alias AI987712; cytokine receptor; HPRL; hPRL receptor; hPRLrI; Lactogen receptor; MFAB; pPRLR-SF; Pr-1; Pr-3; Prl R; PRLR; PRL-R; Prlr-rs1; Prolactin receptor; prolactin receptor 2 precursor; prolactin receptor related sequence 1; prolactin receptor short isoform; RATPRLR; secreted prolactin binding protein
Gene Symbols PRLR
Host Species Mouse
Immunogen Recombinant protein within Human Prolactin Receptor aa 150-350/622.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5618
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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