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  5. Promega InsR Kinase Enzyme System

Promega InsR Kinase Enzyme System

Catalog No. PRV3901 Shop All Promega Corporation Products
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Quantity:
1/Ea.
10 μg

Description

Includes

InsR Kinase Enzyme System (V3901)

  • Kinase: InsR, 10μg (Human, recombinant; amino acids 1011–end). MW: ∽70kDa
  • Substrate: Axltide (KKSRGDYMTMQIG); derived from the mouse Insulin receptor substrate 1 (amino acid 979–989)
  • Reaction Buffer, DTT, MnCl2
ADP-Glo™ Kinase Assay and EGFR Kinase Enzyme System (V9411)
  • 1 x 10μg InsR Kinase Enzyme System (V901) and 1 x 1000 ADP-Glo™ Kinase Assays (V9101)

Recombinant human InsR (amino acids 1011-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. InsR is the insulin receptor tyrosine kinase that is involved in insulin signaling.

  • Easily Screen and Profile InsR Kinase Inhibitors
  • Includes kinase, substrate and reaction buffer
  • Use with ADP-Glo™ Assay for bioluminescent detection of kinase activity

Specifications

Content And Storage <-65°C
For Use With (Application) Involved in Insulin signaling, binding of Insulin to the InsR stimulates Glucose uptake, Insulin receptor signaling helps to maintain fuel homeostasis and prevent diabetes
Quantity 10 μg
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