Invitrogen™ Properdin Polyclonal Antibody

Catalog No.	Quantity
PIPA5109520	100 μL

Catalog No. PIPA5109520 Supplier Invitrogen™ Supplier No. PA5109520

Description

Rabbit Polyclonal Antibody

Immunogen sequence: CPTHGAWATW GPWTPCSASC HGGPHEPKET RSRKCSAPEP SQKPPGKPCP GLAYEQRRCT GLPPCPVAGG WGPWGPVSPC PVTCGLGQTM EQRTCNHPVP QHGGPFCAGD ATRTHICNTA VPCPVDGEWD SWGEWSPCIR RNMKSISCQE IPGQQSRGRT CRGRKFDGHR CAGQQQDIRH CYSIQHCPLK GSWSEWSTWG LCMPPCGPNP TRARQRLCTP LLPKYPPTVS MVEGQGEKNV TFWGRPLPRC EELQGQKLVV EEKRPCLHVP ACKDPEEEEL.

This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections.

Specifications

• Antigen: Properdin
• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1.06 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene: CFP
• Gene Accession No.: P11680, P27918
• Gene Alias: BCFG; Bf; BFD; C3 Proaccelerator; C3/C5 convertase; cfb; CFP; Complement factor P; complement factor properdin; GBG; H2-Bf; PBF2; PFC; PFD; PROPERDIN; properdin factor, complement; properdin P factor, complement
• Gene Symbols: CFP
• Host Species: Rabbit
• Immunogen: Recombinant Protein (or fragment).
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 18636, 299314, 5199
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG