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Invitrogen™ Prosapip1 Polyclonal Antibody
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Catalog No. PIPA556614
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100 μL
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PIPA556614 100 μL
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Catalog No. PIPA556614 Supplier Invitrogen™ Supplier No. PA556614
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: QEFAMKSVGT RTGGGGSQGS FPGPRGSGSG ASRERPGRYP SEDKGLANSL YLNGELRGSD HTDVCGNVVG SSGGSSSSGG SDKAPPQYRE PS Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 91%.

Prosapip1 is a binding partner of the postsynaptic density (PSD) protein ProSAP2/Shank3, a major scaffolding protein in excitatory brain synapses. Prosapip1 is thought to bind ProSAP2/Shank3 through a PDZ domain in ProSAP2/Shank3 and link it in turn to the Spine-associated Rap-Gap (SPAR). Prosapip1 shares significant homology with another PSD protein, PSD-Zip70, with both coding for a Fez1 domain that can be found in a total of four related protein, forming a novel family of scaffolding molecules termed 'Fezzins'. Recent studies show that Prosapip1 can be found in endocrine cells in which it is localized primarily in the hormone-storing compartment of these cells, suggesting that Prosapip1 may have other functions in non-neuronal cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Prosapip1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Lzts3
Gene Accession No. O60299
Gene Alias KIAA0552; Leucine zipper putative tumor suppressor 3; leucine zipper tumor suppressor family member 3; leucine zipper, putative tumor suppressor family member 3; LZTS3; proline rich synapse associated protein interacting protein 1; proline rich synapse associated protein interacting protein 1 (Prosapip1); ProSAP/Shank-interacting protein 1; proSAP-interacting protein 1; PROSAPIP1
Gene Symbols Lzts3
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human LZTS3. Recombinant protein control fragment (Product #RP-95501).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9762
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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