ProSAPiP1 Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS11198R

Catalog No. 50-198-1161

Description

Prosapip1 is a binding partner of the postsynaptic density (PSD) protein ProSAP2/Shank3, a major scaffolding protein in excitatory brain synapses. Prosapip1 is thought to bind ProSAP2/Shank3 through a PDZ domain in ProSAP2/Shank3 and link it in turn to the Spine-associated Rap-Gap (SPAR). Prosapip1 shares significant homology with another PSD protein, PSD-Zip70, with both coding for a Fez1 domain that can be found in a total of four related protein, forming a novel family of scaffolding molecules termed ′Fezzins′. Recent studies show that Prosapip1 can be found in endocrine cells in which it is localized primarily in the hormone-storing compartment of these cells, suggesting that Prosapip1 may have other functions in non-neuronal cells.

Specifications

• Antigen: ProSAPiP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Lzts3
• Gene Alias: KIAA0552; Leucine zipper putative tumor suppressor 3; leucine zipper tumor suppressor family member 3; leucine zipper, putative tumor suppressor family member 3; LZTS3; proline rich synapse associated protein interacting protein 1; proline rich synapse associated protein interacting protein 1 (Prosapip1); ProSAP/Shank-interacting protein 1; ProSAP-interacting protein 1; PROSAPIP1
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 9762
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: O60299
• Gene Symbols: Lzts3
• Immunogen: KLH conjugated synthetic peptide derived from human ProSAPiP1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG