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Description
- Prostaglandin E2 induces cervical ripening and parturition;
- mediates bradykinin-induced vasodilation.
- PGE2 is one of the primary cyclooxygenase products of arachidonic acid and one of the most widely investigated prostaglandins.
- Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation.
- The effects of PGE2 are transduced by at least four distinct receptors designated EP1, EP2, EP3, and EP4.
- Affinity constants (Kd) of PGE2 for these receptors range from 1-10 nM depending on the receptor subtype and tissue.
Specifications
Specifications
| Melting Point | 66°C to 68°C (literature) |
| Color | White |
| Quantity | 5 mg |
| Beilstein | 4709356 |
| Solubility Information | Sparingly soluble in water but freely soluble in organic solvents such as ethanol, methanol, acetone (clear solution), acetonitrile, or DMSO. The solubility of PGE2 in these solvents is at least 10mg/mL |
| Physical Form | Powder |
| Grade | ≥99% |
Safety and Handling
| RTECSNumber | UK8000000 |
| storageNote1 | Sparingly soluble in water but freely soluble in organic solvents such as ethanol, methanol, acetone (clear solution), acetonitrile, or DMSO. The solubility of PGE2 in these solvents is at least 10mg/mL. |
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