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Invitrogen™ Protein APC Recombinant Rabbit Monoclonal Antibody (5F2)
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Catalog No. PIMA538407
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100 μL
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PIMA538407 100 μL
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Catalog No. PIMA538407 Supplier Invitrogen™ Supplier No. MA538407
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Description

Rabbit Recombinant Monoclonal Antibody

This antibody has been tested in direct-ELISA.

This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Protein APC
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 5F2
Concentration 1.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 150mM NaCl and 0.02% sodium azide; pH 7.4
Gene Apc
Gene Accession No. P25054, P70478
Gene Alias adenomatosis polyposis coli; adenomatosis polyposis coli tumor suppressor; adenomatous polyposis coli; adenomatous polyposis coli protein; AI047805; APC; APC, WNT signaling pathway regulator; AU020952; AW124434; BTPS2; CC1; Deleted in polyposis 2.5; DP2; DP2.5; DP3; FAP; FPC; GS; mAPC; Min; multiple intestinal neoplasia; PPP1R46; Protein APC; protein phosphatase 1, regulatory subunit 46; RATAPC; truncated adenomatosis polyposis coli; WNT signaling pathway regulator
Gene Symbols Apc
Host Species Rabbit
Immunogen A synthesized peptide derived from human APC.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 24205, 324
Target Species Human, Rat
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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