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Invitrogen™ Protein APC Monoclonal Antibody (ALi 12-28)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA116631
Description
This antibody does not cross-react with mouse.
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
Specifications
Protein APC | |
Monoclonal | |
1.0 mg/mL | |
PBS with 0.02% sodium azide | |
P25054 | |
Apc | |
Amino acids 1-433 N-terminal fragment of human APC (Adenomutons Polyposis Coli gene Chr 5q) fused to maltose binding protein. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 |
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Immunocytochemistry, Western Blot | |
ALi 12-28 | |
Unconjugated | |
Apc | |
adenomatosis polyposis coli; adenomatosis polyposis coli tumor suppressor; adenomatous polyposis coli; adenomatous polyposis coli protein; AI047805; APC; APC, WNT signaling pathway regulator; AU020952; AW124434; BTPS2; CC1; Deleted in polyposis 2.5; DP2; DP2.5; DP3; FAP; FPC; GS; mAPC; Min; multiple intestinal neoplasia; PPP1R46; Protein APC; protein phosphatase 1, regulatory subunit 46; RATAPC; truncated adenomatosis polyposis coli; WNT signaling pathway regulator | |
Mouse | |
Protein A | |
RUO | |
324 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Safety and Handling
WARNING: Cancer and Reproductive Harm - www.P65Warnings.ca.gov
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