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Invitrogen™ Protein APC Monoclonal Antibody (ALi 12-28)
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Catalog No. AMPA6631
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100 μg
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Catalog No. Quantity
AMPA6631 100 μg
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Catalog No. AMPA6631 Supplier Invitrogen™ Supplier No. MA116631
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Mouse Monoclonal Antibody

This antibody does not cross-react with mouse.

This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Protein APC
Applications ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Immunocytochemistry, Western Blot
Classification Monoclonal
Clone ALi 12-28
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Apc
Gene Accession No. P25054
Gene Alias adenomatosis polyposis coli; adenomatosis polyposis coli tumor suppressor; adenomatous polyposis coli; adenomatous polyposis coli protein; AI047805; APC; APC, WNT signaling pathway regulator; AU020952; AW124434; BTPS2; CC1; Deleted in polyposis 2.5; DP2; DP2.5; DP3; FAP; FPC; GS; mAPC; Min; multiple intestinal neoplasia; PPP1R46; Protein APC; protein phosphatase 1, regulatory subunit 46; RATAPC; truncated adenomatosis polyposis coli; WNT signaling pathway regulator
Gene Symbols Apc
Host Species Mouse
Immunogen N-terminal APC-MBP fusion protein.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 324
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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WARNING: Cancer and Reproductive Harm - www.P65Warnings.ca.gov
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