Invitrogen™ Protein APC Recombinant Rabbit Monoclonal Antibody (8X7Q1)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA535188

Catalog No. PIMA535188

Description

Immunogen sequence: MAAASYDQLL KQVEALKMEN SNLRQELEDN SNHLTKLETE ASNMKEVLKQ LQGSIEDEAM ASSGQIDLLE RLKELNLDSS NFPGVKLRSK MSLRSYGSRE.

This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.

Specifications

• Antigen: Protein APC
• Classification: Recombinant Monoclonal
• Concentration: 1.2 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P25054, P70478, Q61315
• Gene Symbols: Apc
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human APC (NP_0000292).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunoprecipitation, Western Blot
• Clone: 8X7Q1
• Conjugate: Unconjugated
• Gene: Apc
• Gene Alias: adenomatosis polyposis coli; adenomatosis polyposis coli tumor suppressor; adenomatous polyposis coli; adenomatous polyposis coli protein; AI047805; APC; APC, WNT signaling pathway regulator; AU020952; AW124434; BTPS2; CC1; Deleted in polyposis 2.5; DP2; DP2.5; DP3; FAP; FPC; GS; mAPC; Min; multiple intestinal neoplasia; PPP1R46; Protein APC; protein phosphatase 1, regulatory subunit 46; RATAPC; truncated adenomatosis polyposis coli; WNT signaling pathway regulator
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11789, 24205, 324
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid