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Invitrogen™ Protein Tyrosine Phosphatase Polyclonal Antibody
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Catalog No. PIPA5112868
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100 μg
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Catalog No. Quantity
PIPA5112868 100 μg
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Catalog No. PIPA5112868 Supplier Invitrogen™ Supplier No. PA5112868
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Description

Rabbit Polyclonal Antibody

Protein Tyrosine Phosphatase Polyclonal Antibody for Western Blot, ELISA

PRL-3 is a newly identified metastasis-related gene, which codes a 22 KDa non-classical protein tyrosine phosphatase with a C-terminal prenylation motif. It is located at the cytoplasmic membrane when prenylated and in the nucleus when nonpreylated. PRL-3 has at least 75% amino-acid sequence similarity with PRL-1 and PRL-2, the other two members of the PRL family. Recently, Zeng and colleagues found that Chinese hamster ovary cells stably expressing PRL-3 exhibited enhanced motility, invasive activity, and induced metastatic tumor formation in nude mice. And in clinical study, PRL-3 is consistently overexpressed in liver metastasis in colorectal cancer cells. These findings suggest PRL-3 is a new target for the early diagnosis of metastasis as well as the drug discovery.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Protein Tyrosine Phosphatase
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 3.12 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Host Species Rabbit
Immunogen Recombinant Zebrafish Protein tyrosine phosphatase, receptor type, s, a protein (269-424AA).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Zebrafish
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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