Invitrogen™ Prothrombin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579226

Catalog No. PIPA579226

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human plasma. IHC: human colon cancer tissue, human lung cancer tissue. Flow: Human PBMC cell.

Prothrombin or Coagulation factor II, is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.

Specifications

• Antigen: Prothrombin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: F2
• Gene Alias: Activation peptide fragment 1; Activation peptide fragment 2; bovine prothrombin protein; Cf2; Cf-2; coagulation factor 2; coagulation factor II; coagulation factor II (thrombin); coagulation factor II [thrombin]; coagulation factor II, thrombin; F2; FII; kringle-2 domain; fragment-2; prepro-coagulation factor II; preprothrombin; prothrombin; prothrombin B-chain; prothrombin precursor; PT; RPRGL2; serine protease; THPH1; THROMBIN; Thrombin heavy chain; Thrombin light chain
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2147
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and 0.05mg sodium azide
• Gene Accession No.: P00734
• Gene Symbols: F2
• Immunogen: E. coli-derived human Prothrombin recombinant protein (Position: Y67-R124).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG