Invitrogen™ Thrombin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5111397

Catalog No. PIPA5111397

Description

Immunogen sequence: EGVWCYVAGK PGDFGYCDLN YCEEAVEEET GDGLDEDSDR AIEGRTATSE YQTFFNPRTF GSGEADCGLR PLFEKKSLE.

Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.

Specifications

• Antigen: Thrombin
• Classification: Polyclonal
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P00734
• Gene Symbols: F2
• Immunogen: Recombinant Protein corresonding to Human Prothrombin. Recombinant protein control fragment (Product #RP-101519).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Gene: F2
• Gene Alias: Activation peptide fragment 1; Activation peptide fragment 2; Cf2; Cf-2; coagulation factor 2; coagulation factor II; coagulation factor II (thrombin); coagulation factor II, thrombin; F2; FII; prepro-coagulation factor II; Prothombin; prothrombin; prothrombin B-chain; PT; RPRGL2; serine protease; THPH1; thrombin; Thrombin heavy chain; Thrombin light chain
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2147
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov