Invitrogen™ Prothrombin Recombinant Rabbit Monoclonal Antibody (046)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA530564

Catalog No. PIMA530564

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. This antibody has specificity for Mouse Coagulation Factor II/F2.

Prothrombin or Coagulation factor II, is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.

Specifications

• Antigen: Prothrombin
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P19221
• Gene Symbols: F2
• Immunogen: Recombinant Mouse Coagulation Factor II/F2 protein (Met1-Gly618).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA
• Clone: 046
• Conjugate: Unconjugated
• Gene: F2
• Gene Alias: Activation peptide fragment 1; Activation peptide fragment 2; bovine prothrombin protein; Cf2; Cf-2; coagulation factor 2; coagulation factor II; coagulation factor II (thrombin); coagulation factor II [thrombin]; coagulation factor II, thrombin; F2; FII; kringle-2 domain; fragment-2; prepro-coagulation factor II; preprothrombin; prothrombin; prothrombin B-chain; prothrombin precursor; PT; RPRGL2; serine protease; THPH1; THROMBIN; Thrombin heavy chain; Thrombin light chain
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 14061
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid