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Invitrogen™ Protogenin Polyclonal Antibody
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Catalog No. PIPA547671
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100 μg
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Catalog No. Quantity
PIPA547671 100 μg
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Catalog No. PIPA547671 Supplier Invitrogen™ Supplier No. PA547671
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Description

Sheep Polyclonal Antibody

Reconstitute at 0.2 mg/mL in sterile PBS.

Protogenin, encoded by the PRTG gene, is a cell surface protein that belongs to the immunoglobulin superfamily and plays a critical role in neural development. Protogenin is involved in cell adhesion and signaling pathways that regulate processes such as neurogenesis, neuronal migration, and the establishment of neural circuits during embryonic development. Its expression is predominantly observed in the developing nervous system, where it facilitates interactions between cells and the extracellular matrix, contributing to the proper formation of brain structures. Protogenin's function in regulating cellular communication is essential for maintaining the balance between stem cell renewal and differentiation in neural tissues. Dysregulation or mutations in the PRTG gene can lead to developmental abnormalities and have been investigated for their potential connections to neurodevelopmental disorders. Research continues to explore protogenin's mechanisms and interaction networks to better understand its contributions to neural development and its potential as a therapeutic target in developmental disorders.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Protogenin
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene PRTG
Gene Accession No. Q2EY15
Gene Alias A230098A12Rik; IGDCC5; immunoglobulin superfamily, DCC subclass, member 5; protein Shen-Dan; Protogenin; protogenin homolog (Gallus gallus); prtg; shen-dan
Gene Symbols PRTG
Host Species Sheep
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse PRTG Val24-Thr943.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 235472
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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