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Invitrogen™ PRP8 Recombinant Rabbit Monoclonal Antibody (4I1Q8)
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Catalog No. PIMA538118
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PIMA538118 100 μL
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Catalog No. PIMA538118 Supplier Invitrogen™ Supplier No. MA538118
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: HeLa, 293T, Jurkat, Mouse brain, Mouse spleen Immunogen sequence: MADNPSWDGE KTIIITCSFT PGSCTLTAYK LTPSGYEWGR QNTDKGNNPK GYLPSHYERV QMLLSDRFLG FFMVPAQSSW NYNFMGVRHD PNMKYELQLA NPKEFYHEVH RPSHFLNFAL LQEGEVYSAD REDLYA.

Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PRP8
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 4I1Q8
Concentration 1.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Prpf8
Gene Accession No. Q6P2Q9, Q99PV0
Gene Alias 220 kDa U5 snRNP-specific protein; apoptosis-regulated protein 1; apoptosis-regulated protein 2; AU019467; D11Bwg0410e; DBF3/PRP8; H PRPC8; HPRP8; id:ibd1257; ik:tdsubc_2a9; im:7141966; p220; precursor mRNA processing protein; pre-mRNA processing factor 8; pre-mRNA-processing-splicing factor 8; Prp8; PRP8 homolog; PRP8 pre-mRNA processing factor 8 homolog; PRPC8; prpf8; RP13; Sfprp8l; SNRNP220; spl; Splicing factor Prp8; tdsubc_2a9; U5 snRNP-specific protein; U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p; wu:fb37c02; wu:fb73e06; xx:tdsubc_2a9; zgc:56504
Gene Symbols Prpf8
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 2200-2335 of human PRPF8 (Q6P2Q9).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10594, 192159, 287530
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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