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Invitrogen™ PRPF18 Polyclonal Antibody
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Catalog No. PIPA561629
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100 μL
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PIPA561629 100 μL
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Catalog No. PIPA561629 Supplier Invitrogen™ Supplier No. PA561629
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EPGEEDTQND LKVHEENTTI EELEALGESL GKGDDHKDMD IITKFLKFLL GVWAKELNAR EDYVKRSVQG KLNSATQKQT ES Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 99%.

PRPF18 (pre-mRNA-splicing factor 18), also known as HPRP18, is a 342 amino acid protein that localizes to nuclear speckles and plays a role in the second step of pre-mRNA splicing. A member of the PRP18 family, PRPF18 contains seven WD repeats and exists as two alternatively spliced isoforms which are encoded by a gene located on human chromosome 10p13. Chromosome 10 contains over 800 genes and 135 million nucleotides. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. Other chromosome 10 associated disorders include Cockayne syndrome, tetrahydrobiopterin deficiency and trisomy 10.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PRPF18
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PRPF18
Gene Accession No. Q99633
Gene Alias 2810441A10Rik; HPRP18; HPRP18 homolog; Kcrf; Potassium channel regulatory factor; Pprf18; pre-mRNA processing factor 18; pre-mRNA-splicing factor 18; Prp18; PRP18 homolog; PRP18 pre-mRNA processing factor 18 homolog; PRP18 pre-mRNA processing factor 18 homolog (yeast); PRP18 pre-mRNA processing factor 18 homolog(PRPF18); Prpf18
Gene Symbols PRPF18
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PRPF18. Recombinant protein control fragment (Product #RP-104435).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8559
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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