PRPF40A Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-1547	Proteintech Group Inc 173921AP150UL	150 μL

Description

FNBP3, Formin-binding protein 3, is a 957 amino acid protein encoded by the human gene PRPF40A. FNBP3 belongs to the PRPF40 family and contains five FF domains and two WW domains. Nuclear proteins harboring both WW and FF protein interaction modules bind to splicing factors as well as RNA polymerase II and may serve to link transcription with splicing. Through the WW domains, FNBP3 will bind to the Formin proline-rich regions. Also known as Pre-mRNA-processing factor 40 homolog A, FNBP3 binds to WASL/N-WASP (Neuronal Wiskott-Aldrich syndrome protein) complex and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function. FNBP3 is widely expressed in most tissues and is localized to the nuclear speckles.

Specifications

• Antigen: PRPF40A
• Applications: Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: O75400, Q9R1C7
• Gene ID (Entrez): 55660, 56194
• Immunogen: PRPF40A Fusion Protein Ag11290
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: PRPF40A

• Concentration: 0.2 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: Fas ligand associated factor 1, FBP 11, FBP11, FLAF1, FNBP3, Formin binding protein 11, Formin binding protein 3, HIP 10, HIP10, Huntingtin yeast partner A, HYPA, NY REN 6, PRPF40A
• Gene Symbols: PRPF40A
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody