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Invitrogen™ PRPK Monoclonal Antibody (OTI5A5)
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Catalog No. PIMA526956
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100 μL
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PIMA526956 100 μL
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Catalog No. PIMA526956 Supplier Invitrogen™ Supplier No. MA526956
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Description

Mouse Monoclonal Antibody

PRPK Monoclonal Antibody for Western Blot, IHC (P)

Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (PubMed:22912744, PubMed:27903914). The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 (PubMed:22912744, PubMed:27903914). TP53RK has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit OSGEP. Atypical protein kinase that phosphorylates 'ser-15' of p53/TP53 protein and may therefore participate in its activation (PubMed:11546806). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen PRPK
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI5A5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Tp53rk
Gene Accession No. Q96S44
Gene Alias 2810408M09Rik; 4933401B08Rik; 5630401H01Rik; Atypical serine/threonine protein kinase TP53RK; BUD32; C20orf64; dJ101A2; EKC/KEOPS complex subunit TP53RK; mNori-2p; Nori-2; Nori-2p; p53-related protein kinase; PRPK; TP53 regulating kinase; TP53-regulating kinase; TP53RK; transformation related protein 53 regulating kinase; Trp53 regulating kinase; Trp53rk; Trp53tk
Gene Symbols Tp53rk
Host Species Mouse
Immunogen Full length human recombinant protein of TP53RK produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 112858
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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