Invitrogen™ PRPK Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA582542

Catalog No. PIPA582542

Description

Immunogen sequence: AAVIKHRFPK GYRHPALEAR LGRRRTVQEA RALLRCRRAG ISAPVVFFVD YASNCLYMEE IEGSVTVRDY IQSTMETEKT PQGLSNLAKT IGQV.

Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (PubMed:22912744, PubMed:27903914). The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 (PubMed:22912744, PubMed:27903914). TP53RK has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit OSGEP. Atypical protein kinase that phosphorylates 'Ser-15' of p53/TP53 protein and may therefore participate in its activation (PubMed:11546806). [UniProt].

Specifications

• Antigen: PRPK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Tp53rk
• Gene Alias: 2810408M09Rik; 4933401B08Rik; 5630401H01Rik; Atypical serine/threonine protein kinase TP53RK; BUD32; C20orf64; dJ101A2; EKC/KEOPS complex subunit TP53RK; mNori-2p; Nori-2; Nori-2p; p53-related protein kinase; PRPK; TP53 regulating kinase; TP53-regulating kinase; TP53RK; transformation related protein 53 regulating kinase; Trp53 regulating kinase; Trp53rk; Trp53tk
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 112858
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96S44
• Gene Symbols: Tp53rk
• Immunogen: Recombinant protein corresponding to Human TP53RK. Recombinant protein control fragment (Product #RP-89811).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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