Invitrogen™ PRR5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA532179

Catalog No. PIPA532179

Description

Recommended positive controls: Raji. Predicted reactivity: Mouse (90%), Rat (89%), Dog (88%), Pig (87%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

MARK1 (MAP/microtubule affinity-regulating kinase 1) belongs to the MARK family of serine/threonine kinases. MARK family protein kinases phosphorylate microtubule-associated proteins and may play a role in cytoskeletal stability. MARK2 refers to MAP/microtubule affinity-regulating kinase 2 isoform a [Homo sapiens]. EMK (ELKL Motif Kinase) is a small family of ser/thr protein kinases involved in the control of cell polarity, microtubule stability and cancer. Several cDNA clones have been isolated that encoded two isoforms of the human ser/thr protein kinase EMK1 called MARK2. MARK3 was originally identified as a marker that was induced by treatment with DNA damaging agents, and loss of MARK3 was found with carcinogenesis in the pancreas. MARK4 contains an N terminal serine/threonine kinase domain, a central ubiquitin associated domain, and a C terminal KA1 associated kinase domain. RT PCR analysis detects upregulated expression of the gene for MARK4 in nearly all clinical hepatocellular carcinoma cells.

Specifications

• Antigen: PRR5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PRR5
• Gene Alias: Arhgap8; AU043908; C030017C09Rik; C78947; FLJ20185k; PP610; proline rich 5; proline rich 5 (renal); proline-rich protein 5; Protein observed with Rictor-1; Protor1; protor-1; prr5; prr5 {ECO:0000250; Rho GTPase activating protein 8; RP1-181C9.3; UniProtKB:P85299}
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55615
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P85299
• Gene Symbols: PRR5
• Immunogen: Recombinant protein encompassing a sequence within the center region of human Protor 1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG