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Invitrogen™ PRR5 Polyclonal Antibody
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Catalog No. PIPA5120334
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100 μL
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PIPA5120334 100 μL
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Catalog No. PIPA5120334 Supplier Invitrogen™ Supplier No. PA5120334
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Description

Rabbit Polyclonal Antibody

Positive test controls include: 293T, HepG2, SH-SY5Y, Mouse liver, Mouse brain, Rat liver. Immunogen sequence: SRGVTEDYLR LETLVQKVVS PYLGTYGLHS SEGPFTHSCI LEKRLLRRSR SGDVLAKNPV VRSKSYNTPL LNPVQEHEAE GAAAGGTSIR RHSVSEMTSC PEPQGFSDPP GQGPTGTFRS SPAPHSGPCP SRLYPTTQPP EQGLDPTRSS LPRSSPENLV DQILESVDSD SEGIFIDFGR GRGSGMSDLE GSGGRQSVV.

MARK1 (MAP/microtubule affinity-regulating kinase 1) belongs to the MARK family of serine/threonine kinases. MARK family protein kinases phosphorylate microtubule-associated proteins and may play a role in cytoskeletal stability. MARK2 refers to MAP/microtubule affinity-regulating kinase 2 isoform a [Homo sapiens]. EMK (ELKL Motif Kinase) is a small family of ser/thr protein kinases involved in the control of cell polarity, microtubule stability and cancer. Several cDNA clones have been isolated that encoded two isoforms of the human ser/thr protein kinase EMK1 called MARK2. MARK3 was originally identified as a marker that was induced by treatment with DNA damaging agents, and loss of MARK3 was found with carcinogenesis in the pancreas. MARK4 contains an N terminal serine/threonine kinase domain, a central ubiquitin associated domain, and a C terminal KA1 associated kinase domain. RT PCR analysis detects upregulated expression of the gene for MARK4 in nearly all clinical hepatocellular carcinoma cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PRR5
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.89 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene PRR5
Gene Accession No. P85299, Q5FVG6, Q812A5
Gene Alias Arhgap8; AU043908; C030017C09Rik; C78947; FLJ20185k; PP610; proline rich 5; proline rich 5 (renal); proline-rich protein 5; Protein observed with Rictor-1; Protor1; protor-1; prr5; prr5 {ECO:0000250; Rho GTPase activating protein 8; RP1-181C9.3; UniProtKB:P85299}
Gene Symbols PRR5
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 190-388 of human PRR5 (NP_851850.1).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 109270, 315189, 55615
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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