Learn More
Invitrogen™ PRR5 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5120334
Description
Positive test controls include: 293T, HepG2, SH-SY5Y, Mouse liver, Mouse brain, Rat liver. Immunogen sequence: SRGVTEDYLR LETLVQKVVS PYLGTYGLHS SEGPFTHSCI LEKRLLRRSR SGDVLAKNPV VRSKSYNTPL LNPVQEHEAE GAAAGGTSIR RHSVSEMTSC PEPQGFSDPP GQGPTGTFRS SPAPHSGPCP SRLYPTTQPP EQGLDPTRSS LPRSSPENLV DQILESVDSD SEGIFIDFGR GRGSGMSDLE GSGGRQSVV.
MARK1 (MAP/microtubule affinity-regulating kinase 1) belongs to the MARK family of serine/threonine kinases. MARK family protein kinases phosphorylate microtubule-associated proteins and may play a role in cytoskeletal stability. MARK2 refers to MAP/microtubule affinity-regulating kinase 2 isoform a [Homo sapiens]. EMK (ELKL Motif Kinase) is a small family of ser/thr protein kinases involved in the control of cell polarity, microtubule stability and cancer. Several cDNA clones have been isolated that encoded two isoforms of the human ser/thr protein kinase EMK1 called MARK2. MARK3 was originally identified as a marker that was induced by treatment with DNA damaging agents, and loss of MARK3 was found with carcinogenesis in the pancreas. MARK4 contains an N terminal serine/threonine kinase domain, a central ubiquitin associated domain, and a C terminal KA1 associated kinase domain. RT PCR analysis detects upregulated expression of the gene for MARK4 in nearly all clinical hepatocellular carcinoma cells.
Specifications
PRR5 | |
Polyclonal | |
Unconjugated | |
PRR5 | |
Arhgap8; AU043908; C030017C09Rik; C78947; FLJ20185k; PP610; proline rich 5; proline rich 5 (renal); proline-rich protein 5; Protein observed with Rictor-1; Protor1; protor-1; prr5; prr5 {ECO:0000250; Rho GTPase activating protein 8; RP1-181C9.3; UniProtKB:P85299} | |
Rabbit | |
Affinity Chromatography | |
RUO | |
109270, 315189, 55615 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Western Blot, Immunocytochemistry | |
0.89 mg/mL | |
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 | |
P85299, Q5FVG6, Q812A5 | |
PRR5 | |
Recombinant fusion protein containing a sequence corresponding to amino acids 190-388 of human PRR5 (NP_851850.1). | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Safety and Handling
Your input is important to us. Please complete this form to provide feedback related to the content on this product.