Invitrogen™ PRR5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120334

Catalog No. PIPA5120334

Description

Positive test controls include: 293T, HepG2, SH-SY5Y, Mouse liver, Mouse brain, Rat liver. Immunogen sequence: SRGVTEDYLR LETLVQKVVS PYLGTYGLHS SEGPFTHSCI LEKRLLRRSR SGDVLAKNPV VRSKSYNTPL LNPVQEHEAE GAAAGGTSIR RHSVSEMTSC PEPQGFSDPP GQGPTGTFRS SPAPHSGPCP SRLYPTTQPP EQGLDPTRSS LPRSSPENLV DQILESVDSD SEGIFIDFGR GRGSGMSDLE GSGGRQSVV.

MARK1 (MAP/microtubule affinity-regulating kinase 1) belongs to the MARK family of serine/threonine kinases. MARK family protein kinases phosphorylate microtubule-associated proteins and may play a role in cytoskeletal stability. MARK2 refers to MAP/microtubule affinity-regulating kinase 2 isoform a [Homo sapiens]. EMK (ELKL Motif Kinase) is a small family of ser/thr protein kinases involved in the control of cell polarity, microtubule stability and cancer. Several cDNA clones have been isolated that encoded two isoforms of the human ser/thr protein kinase EMK1 called MARK2. MARK3 was originally identified as a marker that was induced by treatment with DNA damaging agents, and loss of MARK3 was found with carcinogenesis in the pancreas. MARK4 contains an N terminal serine/threonine kinase domain, a central ubiquitin associated domain, and a C terminal KA1 associated kinase domain. RT PCR analysis detects upregulated expression of the gene for MARK4 in nearly all clinical hepatocellular carcinoma cells.

Specifications

• Antigen: PRR5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PRR5
• Gene Alias: Arhgap8; AU043908; C030017C09Rik; C78947; FLJ20185k; PP610; proline rich 5; proline rich 5 (renal); proline-rich protein 5; Protein observed with Rictor-1; Protor1; protor-1; prr5; prr5 {ECO:0000250; Rho GTPase activating protein 8; RP1-181C9.3; UniProtKB:P85299}
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 109270, 315189, 55615
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 0.89 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P85299, Q5FVG6, Q812A5
• Gene Symbols: PRR5
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 190-388 of human PRR5 (NP_851850.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov