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Invitrogen™ PRRT2 Monoclonal Antibody (CL4233)
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Catalog No. PIMA531398
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100 μL
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Catalog No. Quantity
PIMA531398 100 μL
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Catalog No. PIMA531398 Supplier Invitrogen™ Supplier No. MA531398
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Description

Mouse Monoclonal Antibody

Immunogen sequence: PKPALQPELP TQEDPTPEIL SESVGEKQEN GAVVPLQAGD GEEGPAPEPH SPPSKKSPPA NGAPPRVLQQ LVEEDRMRRA HSGHPGSPRG SLSRHPSSQL AGPGVEGGEG TQKPRDY Highest antigen sequence indentity to the following orthologs: Rat - 87%, Mouse - 88%.

The proline-rich transmembrane protein 2 (PRRT2) contains a proline-rich domain in its N-terminal half and is predominantly expressed in brain and spinal cord in embryonic and postnatal stages. While little is known of the function of this protein, mutations in PRRT2 have been shown to be the causative gene of paroxysmal kinesigenic dyskinesia, which is characterized by recurrent, brief attacks of abnormal involuntary movements induced by sudden voluntary movements. Recent studies have shown that PRRT2 may also be involved in some forms of benign familial infantile epilepsy (BFIE), an autosomal dominant epilepsy syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PRRT2
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone CL4233
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene PRRT2
Gene Accession No. Q7Z6L0
Gene Alias 1500031I19Rik; AI195361; BFIC2; BFIS2; Dispanin subfamily B member 3; DSPB3; dystonia 10; DYT10; EKD1; FICCA; ICCA; IFITMD1; infantile convulsions and paroxysmal choreoathetosis; interferon induced transmembrane protein domain containing 1; PKC; proline rich transmembrane protein 2; proline-rich transmembrane protein 2; PRRT2; RGD1564195
Gene Symbols PRRT2
Host Species Mouse
Immunogen Recombinant protein fragment of Human PRRT2 (Product #RP-91025)
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 112476
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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