Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA5120752

Invitrogen™ PRRX2 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA5120752
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA5120752 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
This item is not returnable. View return policy
Catalog No. PIPA5120752 Supplier Invitrogen™ Supplier No. PA5120752
Add to Cart
Add to Cart
This item is not returnable. View return policy

Description

Rabbit Polyclonal Antibody

Positive test controls include: NIH/3T3, Mouse brain, Mouse skin, Mouse spleen, Rat testis. Immunogen sequence: QEAAIEQPVA PRPTALSPDY LSWTASSPYS TVPPYSPGSS GPATPGVNMA NSIASLRLKA KEFSLHHSQV PTVN.

The paired-class homeobox genes PRX1 and PRX2 are necessary for craniofacial and limb development and are expressed in similar patterns in the cranial mesenchyme, limb buds, axial mesoderm and branchial arches. These proteins exhibit different patterns of expression, however, in heart and brain tissue. Specifically, PRX1 is expressed in the endocardial cusions, semilunar and atrioventricular valves, whereas PRX2 is initially expressed in a diffuse myocardial pattern and is later expressed in the ventricular septum. Furthermore, PRX2 is never expressed in the brain, whereas PRX1 is expressed in the ventral hypothalamus and in the telencephalon. Murine mutants lacking PRX1 function demonstrate skeletal defects in the skull, limbs, and vertebral column. Mice lacking functional PRX2 alone do not demonstrate skeletal abnormalities, however, PRX1/PRX2 double mutants demonstrate novel abnormalities that are not visualized with the PRX1-deficient mice. Transcripts of neither PRX1 nor PRX2 are detected in normal adult rat pulmonary arteries, however vascular disease induces PRX gene expression wherein they co-localize to sites of Tenascin-C expression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PRRX2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.055 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Prrx2
Gene Accession No. Q06348, Q99811
Gene Alias homeo box of paired rule; homeobox protein S8; LOW QUALITY PROTEIN: paired mesoderm homeobox protein 2; MGC19843; paired mesoderm homeobox protein 2; paired related homeobox 2; paired-like homeodomain protein PRX2; paired-related homeobox protein 2; PMX2; PRRX2; Prx2; PRX-2; S8; surface antigen, homeo box of paired rule; testicular tissue protein Li 148; testicular tissue protein Li 160
Gene Symbols Prrx2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 180-253 of human PRRX2 (NP_057391.1).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 113931, 20204, 51450
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.