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PRSS2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501980915
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50-198-0915 100 μL
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Catalog No. 50-198-0915 Supplier Bioss Supplier No. BS10501R
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Description

Rabbit Polyclonal Antibody

This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.

Specifications

Antigen PRSS2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene PRSS2
Gene Accession No. P07478
Gene Alias Anionic trypsin II; Anionic trypsin-2; Anionic trypsinogen; EC 3.4.21; EC 3.4.21.4; MGC111183; MGC120174; MGC120175; pancreatic trypsin 2; pancreatic trypsin II; Pretrypsinogen II; protease serine 2 preproprotein; protease, serine 2; protease, serine, 2; protease, serine, 2 (trypsin 2); PRSS2; Ptryss2; Serine protease 2; Ta; Tesp4; Try2; TRY8; TRYP; TRYP2; trypsin 2; Trypsin II; trypsin Trypsin II; Trypsin-2; trypsinogen 2; trypsinogen 20
Gene Symbols PRSS2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human PRSS2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5645
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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