Invitrogen™ PRSS27 Monoclonal Antibody (6F11)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA522709

Catalog No. PIMA522709

Description

Peptide Sequence: QLVQPGPHAM YARVRQVESN PLYQGTASSA DVALVELEAP VPFTNYILPV CLPDPSVIFE TGMNCWVTGW GSPSEEDLLP EPRILQKLAV PIIDTPKCNL LYSKDTEFGY.

PRSS27, also known as Marapsin, is a gene located on chromosome 16p13.3 that encodes a serine protease enzyme. This protein is part of the trypsin-like serine protease family, which is characterized by a catalytic triad essential for proteolytic activity. PRSS27 is primarily expressed in the epidermis and other epithelial tissues, such as the salivary glands and pancreas. It plays a role in various physiological processes, including digestion, inflammation, and immune response regulation. In the skin, PRSS27 is involved in keratinocyte differentiation and the maintenance of skin barrier function. Dysregulation or altered expression of PRSS27 has been associated with inflammatory skin conditions, such as psoriasis, where it may influence the inflammatory cascade and contribute to disease pathogenesis. Research into PRSS27 continues to explore its potential role in epithelial homeostasis and as a therapeutic target for skin-related and other inflammatory disorders.

Specifications

• Antigen: PRSS27
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q9BQR3
• Gene Symbols: PRSS27
• Immunogen: PRSS27 (NP_114154, 94 a.a. ~ 203 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA, Western Blot
• Clone: 6F11
• Conjugate: Unconjugated
• Gene: PRSS27
• Gene Alias: CAP-2; CAPH2; channel-activating protease 2; channel-activating protease 2-like protein; EC 3.4.21; EC 3.4.21.4; EC 3.4.21.43; marapsin; Mpn; MPNMarapsin; Pancreasin; protease, serine 27; PRSS27; Serine protease 27; UNQ1884/PRO4327
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 83886
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid