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Invitrogen™ PRTFDC1 Monoclonal Antibody (07)
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Catalog No. PIMA541074
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100 μL
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PIMA541074 100 μL
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Catalog No. PIMA541074 Supplier Invitrogen™ Supplier No. MA541074
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Description

Mouse Monoclonal Antibody

PRTFDC1 Monoclonal Antibody for Western Blot, ELISA

Phosphoribosyl transferase domain containing 1 (PRTFDC1) is highly homologous to the hypoxanthine phosphoribosyltransferase (HPRT1) and may have arisen from a gene duplication event of a common ancestor gene. Recently, it was shown that CpG islands in the PRTFDC1 promoter could be hypermethylated in ovarian cancers and oral squamous-cell carcinomas (OSCC), leading to gene silencing. Restoration of PRTFDC1 expression in OSCC inhibited cell growth in colony-formation assays, while knockdown of PRTFDC1 expression in OSCC that expressed the gene promoted cell growth. These results suggest that PRTFDC1 can act as a tumor-suppressor gene. At least three isoforms of PRTFDC1 are known to exist.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PRTFDC1
Applications ELISA, Western Blot
Classification Monoclonal
Clone 07
Conjugate Unconjugated
Formulation PBS with no preservative
Gene PRTFDC1
Gene Accession No. Q9NRG1
Gene Alias HHGP; phosphoribosyl transferase domain containing 1; phosphoribosyltransferase domain-containing protein 1; PRTFDC1
Gene Symbols PRTFDC1
Host Species Mouse
Immunogen Recombinant Human PRTFDC1 protein.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56952
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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