Invitrogen™ PRUNE2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA554592

Catalog No. PIPA554592

Description

Immunogen sequence: LNDEGKLSIT LVGSSVLASE DKTLESAVVK VINPVEQSDA NVEFRESSSS LVLKEILQEA PELITEQLAH RLRGSILFKW MT Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 83%.

PRUNE2 gene, also named BMCC1, encodes protein prune homolog 2. PRUNE2 gene are overlapping with PCA3, one of the most prostate cancer specific markers. PRUNE2 may play an important role in regulating differentiation, survival and aggressiveness of the tumor cells. Besides its high level of expression seen in the nervous system (brain, cerebellum and spinal cord), it is also expressed at high levels in noneuroblastoma, rhabdomyosarcoma, melanoma and some osteosarcoma cell lines, whereas at only low levels in cancer cell lines of liver, breast, thyroid and colon. The Calculated molecular weight of this protein is 340 kDa.

Specifications

• Antigen: PRUNE2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PRUNE2
• Gene Alias: 6330414G02Rik; A214N16.3; A230083H22Rik; A330102H22Rik; bA214N16.3; BCH motif-containing molecule at the carboxyl terminal region 1; Bmcc1; BNIP2 motif containing molecule at the carboxyl terminal region 1; BNIP2 motif-containing molecule at the C-terminal region 1; BNIPXL; C9orf65; DKFZp762K117; KIAA0367; mKIAA0367; neuronal protein; olfaxin; protein prune homolog 2; prune homolog 2; prune homolog 2 (Drosophila); PRUNE2; RGD1311350; RP11-214N16.3; RP11-58J3.2; truncated PRUNE2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 158471
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8WUY3
• Gene Symbols: PRUNE2
• Immunogen: Recombinant protein corresponding to Human PRUNE2. Recombinant protein control fragment (Product #RP-93019).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov