Invitrogen™ PRX Polyclonal Antibody

Catalog No.	Quantity
PIPA551646	100 μL

Catalog No. PIPA551646 Supplier Invitrogen™ Supplier No. PA551646

Description

Rabbit Polyclonal Antibody

Immunogen sequence: MKVPDMKLPE IKLPKVPEMA VPDVHLPEVQ LPKVSEIRLP EMQVPKVPDV HLPKAPEVKL PRAPEVQLKA TKAEQAEGME FGFKMPKMTM PKLGRAESPS RGKPGEAGAE VSGKLVTLPC LQPEVDGEAH VGVPSLTLPS VELDL Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 68%.

Periaxin is a protein that in humans is encoded by the PRX gene. This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein). Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy.

Specifications

• Antigen: PRX
• Applications: Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: PRX
• Gene Accession No.: Q9BXM0
• Gene Alias: CMT4F; KIAA1620; L-Periaxin; periaxin; PRX
• Gene Symbols: PRX
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human PRX. Recombinant protein control fragment (Product #RP-100995).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 57716
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG