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PSA Monoclonal Antibody (EP1588Y), Invitrogen™

Catalog No. PIMA514470
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Catalog No. Quantity
PIMA514470 1 mL
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Catalog No. PIMA514470 Supplier Thermo Scientific Supplier No. MA514470

Description

Rabbit Monoclonal Antibody

MA5-14470 targets Prostate Specific Antigen in IHC (P), ICC/IF and WB applications and shows reactivity with Human samples, however this antibody is not recommended for human colon and mouse prostate tissue sections. This antibody does not react with rat tissue in Western blot applications. The MA5-14470 immunogen is a synthetic peptide corresponding to residues near the C-terminus of human PSA.

PSA is a chymotrypsin-like serine protease (kallikrein family) produced by the prostate epithelium, and is abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. PSA is used to confirm prostatic acinar cell origin in primary and metastatic carcinoma and to rule out non-prostatic carcinoma mimics.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PSA
Applications Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone EP1588Y
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation tissue culture supernatant with 15mM sodium azide
Gene KLK3
Gene Accession No. P07288
Gene Alias Antigen; antigen, prostate specific; APS; Fletcher factor; gamma-seminoprotein; hK3; Kal3; Kal-3; Kallikrein 3; kallikrein 3, plasma; kallikrein B, plasma 1; kallikrein related peptidase 3; kallikrein-3; Kallikrein-3 (KLK3); kallikrein-related peptidase 3; Kalp1; KALP15; Kininogenin; KLK2A1; Klk3; KLK-3; Klkb1; P-30 antigen; Pk; Plasma kallikrein; Plasma kallikrein heavy chain; Plasma kallikrein light chain; Plasma prekallikrein; prostate specific antigen; prostate-specific (APS); prostate-specific antigen; PSA; Semenogelase; seminin
Gene Symbols KLK3
Host Species Rabbit
Immunogen A synthetic peptide corresponding to residues near the C-terminus of human PSA
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 354
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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