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Invitrogen™ PSAP Polyclonal Antibody
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Catalog No. PIPA582153
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100 μL
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PIPA582153 100 μL
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Catalog No. PIPA582153 Supplier Invitrogen™ Supplier No. PA582153
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TNSTFVQALV EHVKEECDRL GPGMADICKN YISQYSEIAI QMMMHMQPKE ICALVGFCDE VKEMPMQTLV PAKVASKNVI PALELVEPIK KHEVPAKSDV YCEVCEFLVK EVTKLIDNNK TEKEILDAFD KMCSKLPKSL SEE Highest antigen sequence indentity to the following orthologs: Rat - 56%, Mouse - 51%.

PSAP is a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PSAP
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Psap
Gene Accession No. P07602
Gene Alias A1 activator; AI037048; Cerebroside sulfate activator; Co-beta-glucosidase; Component C; CSAct; Dispersin; GLBA; Glucosylceramidase activator; Proactivator polypeptide; prosaposin; prosaposin (sulfated glycoprotein, sphingolipid hydrolase activator); Protein A; Protein C; Psap; SAP1; SAP-1; SAP-2; Saposin-A; Saposin-B; Saposin-B-Val; Saposin-C; Saposin-D; Sgp1; SGP-1; SGP1A; snoRNA MBII-198; Sphingolipid activator protein 1; Sphingolipid activator protein 2; sphingolipid activator protein-1; sulfated glycoprotein 1; Sulfatide/GM1 activator
Gene Symbols Psap
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PSAP. Recombinant protein control fragment (Product #RP-102428).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5660
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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